There is so much excitement and cutting-edge research on anti-aging supplements. That being said, there are also a ton of awesome companies developing one-of-a-kind, research-backed products. This article will help you determine the best NMN supplements to boost longevity and explain the science behind NMN.
- NMN is an anti-aging supplement that reduces cellular aging and increases levels of NAD+.
- The best NMN supplements focus on purity, proper dosage, and quality of ingredients.
- Our top three NMN supplements include Liposomal NMN Synergy™, NMN 300, and NAD+ Platinum.
What is NMN?
You may remember from high school biology a molecule called NAD+ that was involved in the Krebs Cycle. You know, the series of reactions in the mitochondria through which almost all living cells produce energy in aerobic respiration. Well, NMN is short for nicotinamide mononucleotide and is a direct precursor to NAD.
Essentially, our cells use NMN to make NAD. NMN supplementation can potentially increase NAD levels, which is why it is categorized as a “NAD booster.”
Why is this important?
To grossly oversimplify complex scientific processes, NMN plays a critical role in energy production. Practically, that means NMN supplements can be used for anti-aging efforts to boost longevity.
Let’s go a little further into the specifics of NMN as an anti-aging supplement. NMN provides fuel for a class of proteins called sirtuins. Sirtuins are enzymes that help turn metabolic proteins on and off as needed. They’re responsible for regulating tons of proteins that influence aging, inflammation, detoxification, stress resistance, metabolism, circadian rhythms, and more.
More specifically to longevity, these sirtuins can “turn on” proteins linked to longevity genes that keep us feeling young and spry. NMN can increase NAD levels, which increases sirtuin activity, which, researchers are discovering, is one of the key mechanisms for slowing down aging.
Why Take NMN Supplements?
The research into NMN supplements and their potential health benefits is still in its early stages.
However, here is the information we do know.
Reduces Cellular Aging
NMN supplements boost NAD levels, and high levels of NAD activate sirtuins. As we know, sirtuins are proteins that have many crucial functions, such as DNA repair, regulating inflammation, and cell metabolism.
Boosting NAD levels using NMN has been shown to increase NAD levels and improve the hallmarks of aging in yeast, flies, and mice. On a similar note, taking NMN has been shown to increase NAD levels in humans as well.
Improves Cognition in Elderly
Scientists are researching the potential role of NMN supplements in improving brain health and function regarding dementia. A handful of animal studies have looked at how feeding NMN supplements to animals has a positive impact. For example, it improves blood flow in the brain and reduces the number of abnormal proteins that build up in Alzheimer’s.
Improves Aerobic Capacity and Muscle Function
A double-blind, placebo-controlled trial in 2021 looked at giving NMN supplements to amateur runners. They showed that the runners given NMN over a 6-week period had a better aerobic performance. The researchers suggest that this is probably because NMN increases the utilization of oxygen by muscle cells.
Improves Insulin Sensitivity
As we age, our cells become less sensitive to the action of insulin. The damaging effects of this are evident in people with uncontrolled diabetes.
Studies have shown that NMN supplements could improve insulin sensitivity in muscle cells and are seen as a possible natural option for keeping sugar levels in check.
How to Find the Best NMN Supplement?
How do you ensure the NMN supplement you chose is trustworthy and of good quality? Here are the markers we look at when deciding which supplements to recommend.
Purity – 98% purity NMN is the benchmark level you should look for.
Dose – NMN is a dietary supplement, so no specific recommended dose exists. With that said, the best NMN supplements stick to a range of 250 to 500mg because this dose has the lowest side effect profile while still having an impact.
Quality – During manufacturing, small amounts of inactive ingredients are added to prevent the machines from getting stuck. These are called “flow agents.” The top NMN supplements avoid the use of magnesium stearate.
Manufacturing standards – Manufacturers in the US and Europe must comply with good manufacturing practices (GMP) and also have inspections by regulatory agencies such as the FDA.
Top Three NMN Supplements
Liposomal NMN Synergy™ is a potent formula containing nicotinamide mononucleotide (NMN) and trimethylglycine (TMG) to support healthy aging and cellular function. TMG is a methyl donor that supports the action of NMN. Liposomal NMN Synergy™ is the only NAD precursor using a liposome delivery for enhanced bioavailability.
NMN nicotinamide mononucleotide performance supplement comes in powder-filled capsules for both women and men. It contains 300 mg of NMN per capsule to support mitochondrial integrity and cellular recovery.
NAD+ Platinum is a blend of NMN, methylation cofactors, and sirtuin activators. It combines the action of 3 separate products (NAD Gold, Methyl Charge, and The One) to offer the most synergistic and complete longevity formula available. It requires refrigeration upon receipt.
Work with Peak Health Institute
It’s important to appreciate that not all NMN supplements are the same. If you need help deciding which is the best NMN supplement to boost longevity, reach out to our experts at Peak Health Institute or shop our certified supplements! Depending on which brand you opt to go for, there could be a big difference in quality and dose.